The Nat E. Hyder Papers contain five account books, genealogical notes, newspapers, correspondence, photographs, legislative bills, a Congressional report, a claim for damages, 125 powers of attorney, memorabilia, and miscellaneous publications. In addition to these documents, there are miscellaneous records that were incorporated into the Hyder papers by the staff of the B. Carroll Reece Museum prior to the collection's transfer to the archives. The documents date from 1802 to 1930, but the bulk of the papers encompass 1870-1900.
The account books document Hyder's career as a Carter County surveyor and "medical" doctor between 1874 and 1900; the books include patient names, dates, type of service, fees, and the balances of various accounts. The genealogical notes describe the histories of several Carter County families, including Taylor, Patton, Tipton, Jackson, Dulane, and McNabb families. The correspondence, legislative bills, powers of attorney, claim for damages, and the Congressional report document claims made against the United States government for supplies and services that were rendered by Carter County residents to northern troops during the Civil War. The photographs depict Hyder's activities with the 13th Volunteer Tennessee Cavalry and the Independent Order of Odd Fellows. The miscellaneous documents and newspapers document turn-of-the-century events and activities in Johnson City, Tennessee.